Friday, May 22, 2020
Addiction develops as an emotional crutch, impacting character development. This addiction could potentially be a result of three main factors: setting and age, key personal relationships and key tragic events. Each of these elements have a level of responsibility in the development and overcoming of the addiction for Kayla in The disappearing Girl and Rachel in The Girl on the Train. However some of the elements have more of a responsibility than the others. Kayla in The Disappearing Girl is a female adolescent living in the United States of America in the twenty first century. Much like The Disappearing girl, The Girl on the Train is also set in the twenty first century. However it is set in London and the main character, Rachel, is inÃ¢â¬ ¦show more contentÃ¢â¬ ¦2015. p8). Subsequently Rachel uses alcohol to feel in control. She is unemployed and was left by her husband, Tom. She does not feel in control of her employment or relationships but feels that she can control how much she alcohol she consumes. Substance abuse is also used as an emotional crutch. In The Disappearing Girl, bulimia nervosa is used to relieve her of the emotions of mourning the death of her father and to comfort her from the constant criticisms of her mother, Ã¢â¬Å"the emotional release I felt brought an overpowering sense of reliefÃ¢â¬ (Wood. 2015. p8). Much like Kayla, Rachel uses alcohol to help feel better about herself and to help her forget her pain, Ã¢â¬Å"Some days I feel so bad that I have to drink; some days I feel so bad I canÃ¢â¬â¢t.Ã¢â¬ (Hawkins. 2015. P31). Addictions develop as an emotional crutch often after one experiences a traumatic or tragic event. this seems to be the case when looking at both novels. In The Disappearing Girl, Kayla suffers the death of her father. The two had a very close bond therefore this tragedy took a deep emotional toll on Kayla. The death of her father left her at the mercy of her cruel mother and her own self-hatred Ã¢â¬Å"I never realised how much of a buffer he was until he was goneÃ¢â¬ (Wood. 2015. P6). After his death she became more weight conscious and her self-esteem worsened. Due to this she developed anorexia nervosa and then bulimia nervosa to cope with the loss of her father. Similarly to Kayla, Rachel also suffers the deathShow MoreRelatedThe Middle Child Named Edward Jimenez948 Words Ã |Ã 4 PagesMr. and Mrs. Jimenez have three kids, two boys and one girl. Oldest one named Edwin Jimenez, Youngest one named Emely Jimenez. There goes me the middle child named Edward Jimenez. My brother and sister were born here in America where my parents had to travel all the way from Dominican Republic. I consider myself being more Dominican than American due to the fact my whole family speaks Spanish and share many things about our culture. When my parents came here to America, my father couldnÃ¢â¬â¢t go to schoolRead More Innocence In The Catcher In The Rye by J.D. Salinger Essay examples1412 Words Ã |Ã 6 Pageswould have to die before growing up. Despite his death, Holden continues to think about Allie and does not Ã¢â¬Å"enjoy seeing him in that crazy cemeteryÃ¢â¬ ¦surrounded by dead guys and tombstonesÃ¢â¬ (Salinger 155). Allie is someone that Holden formed a personal relationship with, and because of his death, Holden experiences a change in his perception of society and life. This change leads to HoldenÃ¢â¬â¢s desire to keep those around him constant and everlasting to prevent another individual he is close with to dieRead MoreEssay on Theodore Bundy1163 Words Ã |Ã 5 PagesTheodore Bundy One of the most famous killers of all time, Theodore Bundy vented his rage on women, mostly college girls, all the while maintaining the facade of a perfectly normal, intelligent, model citizen. His traveling ways, clever tactics, and thorough body disposal methods make it difficult to even say how many women Bundy killed during his reign, but he was definitely one of the most prolific and frightening serial killers of all time. Bundys rampage mostRead MoreEssay One With the Animals: Symbolism of the Animals in The Wars 1139 Words Ã |Ã 5 PagesAnimals come to represent, both purity and the relationship human beings have with the world. Animals play a key role in Timothy FindleyÃ¢â¬â¢s novel, The Wars, whether its for the interference, necessity, affection or compassion towards the characters. In The Wars, several characters share this close bond with the animals, that serve to emphasize the different qualities of each characterÃ¢â¬â¢s personality. The animals connect with the main character, Robert Ross, in ways that reflect his uncommon characterRead MoreFeminist Views and Author Connections in The Bean Trees1552 Words Ã |Ã 6 PagesFeminist Views and Author Connections in The Bean Trees Barbara Kingsolver, author of The Bean Trees, emphasizes her societal views throughout the novel and tells the story in the first person narrative of Taylor Greer, a practical but spirited girl trying to escape her simple and somewhat boring life to a more exciting one. TaylorÃ¢â¬â¢s character reflects Kingsolver in the way that they both focus on creating a more just society in which women are treated as equals and have the same rights as men.Read MoreHow Effectively Does the Opening Chapter of Pride and Prejudice Introduce the Reader to the Central Characters and Concerns of the Novel?1283 Words Ã |Ã 6 Pagesintroduced to Mr Bennet and Mrs Bennet. Through these characters, the reader learns about Mrs Bennets biggest concern; to marry off all her daughters. The themes of the novel are mostly related to the title, ÃâPride and Prejudice, there is an element of personal pride amongst the characters and also prejudice, particularly with Darcy and Elizabeth. The first chapter bri ngs in the reader into the world of social class importance, marriage and womens role in the 19th century, which is satirized by AustenRead MoreEssay about Jostein Gaardners Sophies World1694 Words Ã |Ã 7 PagesA novel that focuses throughout the history of philosophy, SophieÃ¢â¬â¢s World by Jostein Gaardner, goes through over two-thousand years of philosophical history with a young girl names Sophie. A story with a twist, Gaardner is able to study the history of philosophy, focusing deeply even towards its outreach to the development of psychology. This novel is one designed to please children and adults alike to learn more and discover deeper meaning into philosophical thought. The story begins by focusingRead MoreThe Traumitized Life of Holden1747 Words Ã |Ã 7 Pagesmisery and agony from the past. From a psychoanalytical perspective, readers can understand HoldenÃ¢â¬â¢s behavior throughout the novel as a troubled teenager trying to avoid growing up and demonstrates reck less actions like consuming alcohol, immature relationships with women, not committing to school and silly fantasy thoughts to cope with his life. HoldenÃ¢â¬â¢s childish actions demonstrate he cannot face the responsibilities of life. The novel is written in first person point of view to allow readers to observeRead MoreEssay about Full House: How It Represents the Late 80s/Early 90s4461 Words Ã |Ã 18 PagesTraditional Themes of Morality, Late Eighties Mentality The transition from the multicultural era of the eighties to the postnetwork era of the nineties triggered abrupt changes in American media and culture.  From fashions to family life, relationships, and attitudes, many new cultural elements subsequently changed television portrayals of ordinary American culture within this time period. More specifically, the culture of the eighties is often characterized by the rise of MTV and megastars,Read MoreThe Importance Of Personal Identity In Giovannis Room1853 Words Ã |Ã 8 Pagesthrough a private voyage that includes more than just drive from one point to an alternative point, it must also lead to a variation within and an acceptance of who one really is. In Giovannis Room, the main character David travels a journey pursuing personal growth and acceptance to who he really knows he is. A white, homosexual man, David finds himself stuck in a certain personality one that is straight, masculine and white. An American ideal which he knows d oes not define who he really is. David devotes
Sunday, May 10, 2020
Brochure More information from http://www.researchandmarkets.com/reports/2412467/ Country Road Limited (CTY) - Financial and Strategic SWOT Analysis Review Description: Summary Country Road Limited (Country Road) is a retailer of apparel, homewares and related accessories. The company operates as a subsidiary of Woolworths Holdings Limited. Country Road designs, wholesales, and licenses apparel products. Its products include apparels for men, women and children, gift cards, gift wraps, and tailoring services. The company sells its products primarily through retail stores, department and specialty stores. It operates an online site, 60 retail stores and 80 concession outlets under the Country Road and Trenery brands. The company hasÃ¢â¬ ¦show more contentÃ¢â¬ ¦- Key elements such as SWOT analysis, corporate strategy and financial ratios and charts are incorporated in the profile to assist your academic or business research needs. Contents: List of Tables List of Figures Section 1 - About the Company Country Road Limited - Key Facts Country Road Limited - Key Employees Country Road Limited - Major Products and Services Country Road Limited - History Country Road Limited - Company Statement Country Road Limited - Locations And Subsidiaries Head Office Other Locations Subsidiaries Section 2 Ã¢â¬â Company Analysis Country Road Limited - Business Description Country Road Limited - SWOT Analysis SWOT Analysis - Overview Country Road Limited - Strengths Strength - Strong Liquidity Position Strength - Recognized Brand Portfolio Strength - Synergy with Parent Country Road Limited - Weaknesses Weakness - Limited Operating Margin Country Road Limited - Opportunities Opportunity - Rising Demand for Private Label Goods Opportunity - Growing E-Retail Industry Opportunity - Positive Outlook of Australian Economy Opportunity - Strategic Acquisition Country Road Limited - Threats Threat - Highly Competitive Environment Threat - Ris ing Labor Wages Threat - Dynamic nature of Fashion Industry Threat - Reduced Consumer Spending Country Road Limited - Key Competitors Section 3 Ã¢â¬â Company Financial Ratios Financial Ratios - Capital Market Ratios Financial Ratios - Annual Ratios Performance Chart Financial PerformanceShow MoreRelatedCountry Road Limited6314 Words Ã |Ã 26 Pages| 2010 | | | | | Country Road Limited | Business analysis and valuation | * Table of Contents Executive summary 3 1. The Retail Industry amp; its Prospects 4 1.1 Current amp; Future Overview 4 2 Corporate strategy 4 3 Earnings Manipulation Assessment amp; Findings 5 4 The Facts: Financial Ratio Analysis 6 5 Profitability and Operating management of CR 6 5.1 Dupont System Analysis 6 5.2 CRÃ¢â¬â¢s operating management 8 6 Investment management 8 6.1 WorkingRead MoreCountry Road Analysis2910 Words Ã |Ã 12 PagesINTRODUCTION Country road has always been one of Australia leading premium stockists of apparel and home wares. Country Road began as a small manufacturer but expanded and diversified to become a leading wholesaler/retailer of apparel and home wares in the Australian market. The great success of this fueled the company into an expansionary strategy into the lucrative yet highly competitive US markets and also further along the way into the Asian markets. The strategy of international expansion intoRead MoreCountry Road Essay example1130 Words Ã |Ã 5 PagesCountry Road has been an iconic Australian brand for 36 years, building its success on its high quality and unique designs that look effortlessly casual yet stylish. Following the high financial performances of their Australian stores, Country Road decided to embark into the United States of America (US) in 1989, in hope of realising the financial gains they saw here. Unfortunately, their strategies didnÃ¢â¬â¢t work, and they found obstacle s which hindered their success in the US. This essay examinesRead MoreCountry Road Essay examples4514 Words Ã |Ã 19 PagesExecutive summary This assignment is generally based on understanding and sighting the performance of the Country road. This report mainly concern with exploring and reinforcing the principles of financial and management accounting from a user perspective. It helps to emphasis on business reporting for decision making in a systematic, integrated and cohesive approach. The objective of this report is to provide end-user with a guide to sources of financial statementÃ data to highlight and define theRead MoreGlobal Marketing Environment and Country Road2827 Words Ã |Ã 12 Pages1.01. Introduction: In this report I will analyse Country Road Clothing Company (CR) and the CR customer. Specifically, I will be analysing the marketing environment and Country RoadÃ¢â¬â¢s approach to this environment and how CR market to their customers. I will look it why the marketing in Australia is so successful but how this same success was not translated in overseas markets. I will also discuss the different macro and micro environmental influences to this failure in the U.S. markets and makeRead MoreThe Road Networks Across China Essay1027 Words Ã |Ã 5 PagesThe map below shows an overview of the road networks across china. It is clearly understandable from the graph that eastern part of China is mostly covered through a huge networks and channels of roads and highways. Contrarily, the western parts of China are still to be developed though roads and highway networks. The differences are based on the fact that the eastern parts being close to the sea act as the main hub for transportation of tradable goods as most of the transportation is carried outRead MoreThe Gossip Of The Cyclers1454 Words Ã |Ã 6 Pagesarticles covered everything from cycling club politics to trends in cycling. One of the more important things written about was the Good Roads Movement. The Good Roads Movement was a movement started by cyclists in the 1880Ã¢â¬â¢s that rallied for, and eventually helped create the roads that are used today, or at least the structure of some of the roads. The Good Roads Movement had a variety of people involved, but a large organization involved was the League of American Wheelmen. INFORMATION ABOUT LEAGUERead MoreThe War Of 1812 And The Civil War959 Words Ã |Ã 4 Pagessystem growth. Roads and canals will shorten distances, effortless way to get somewhere, and facilitate commercial and personal communication. The first roads in America were developed by early settlers. Ã¢â¬Å"The National Road was the first highway built entirely with federal funds. The road was authorized by Congress in 1806 during the Jefferson AdministrationÃ¢â¬ (Ã¢â¬Å"The National RoadÃ¢â¬ par. 1). The first 10 miles of roads were built. Wagons were slow and very difficult to use on dirt roads because of theRead MoreThe Construction Of The Alaskan Highway1136 Words Ã |Ã 5 Pagesdifficult than originally anticipated. In March 1942, the first blades dug into the ground. This was a very daunting task; a task that only the US Army Corps of Engineers could handle. Through some of the toughest and most desolate wilderness this country has to offer. Through freezing temperatures to swamp like conditions the Engineers prevailed, The Alaskan Highway was built. It was not without its man y difficulties, additional missions added to the already daunting task, trial and error situationsRead MoreUse Of Screed Plate Of Paver Machine From Sticky Asphalt At Gujarat Power Engineering Research Institute1693 Words Ã |Ã 7 Pageswe express my indebtedness to the Ã¢â¬Å"ALMIGHTYÃ¢â¬ for all His blessing and kindness. LIST OF FIGURES Fig. No. Fig. Name Page No. 1 Indian road making rate 12 2 CompanyÃ¢â¬â¢s logo 15 3 Paver machine 18 4 Working of paver machine 21 5 Working of paver machine 22 6 Use of paver machine 24 7 Asphalt making plant 29 8 Use of asphalt plant 33 9 Problems in company 34 10 Problem definition 38 11 Made
Wednesday, May 6, 2020
Which is the more reliable source for investigating peopleÃ¢â¬â¢s attitudes in 1910 towards the campaign Free Essays
Source D is a newspaper report about a demonstration by women in London in 1910; we can infer these women were Suffragettes as it was around the time of the peak in Suffrage activity and the obscenities mentioned are more closely related to those of the Suffragettes than any other group. However the author of the article, mistakenly, refers to them throughout the report as Suffragists. This shows the writerÃ¢â¬â¢s lack of knowledge on the matter, and their ignorance to the issue leads us to believe they donÃ¢â¬â¢t even know the full story. We will write a custom essay sample on Which is the more reliable source for investigating peopleÃ¢â¬â¢s attitudes in 1910 towards the campaign? or any similar topic only for you Order Now We can also infer from this that the author was anti all women suffrage, and all groups of women who wanted the vote; Suffragettes and Suffragists. It is very likely that the author of the newspaper article in Source D was a man. We can deduce this, as around the time it was written, we know men were considered more important and therefore it is unlikely there would have been many female reporters. We can also deduce this because, although there were some women who were anti-suffrage, the majority were indeed men. Knowing this about the author would lead us to believe the article is biased against women and would therefore present them in the most negative light. The article has a rather gossipy tone to it, and although some strong facts are put across (the Suffragettes did storm the House of Commons, arrests were made, the women were led by Mrs Pankhurst and they did come from the Council of War at Caxton Hall), most of it is opinion, for instance, Ã¢â¬Å"It was a picture of shameful recklessnessÃ¢â¬ ¦Ã¢â¬ , is a point of view, not a fact. However this is helpful in giving us an insight into the opinions of the public too, around this time. The article was written for the Daily Sketch, a tabloid; the author would have been writing to sell papers, he would therefore be writing things that would appeal to the public and please them. We can therefore infer from the source that the public views were also anti-suffrage. Source E is a postcard issued by the Suffragettes in 1910. It is obviously a piece of propaganda as it was made by the Suffragettes and is an argument in favour of votes for women. The point it is arguing and is also proving is that, you can be a decent woman (a doctor, a nurse or a mother) and not receive the vote, but an indecent man (a lunatic, a drunkard) can receive it. Both Sources are very reliable and they are both useful in showing the reader vastly different attitudes about the campaign to gain women the vote. Source E is very good at showing us the positive side to the argument. It is very reliable in showing what Suffragettes attitudes were, however, it is purely opinionated, and being a piece of propaganda it gives us no insight into the publicÃ¢â¬â¢s view of the matter. That is why Source D is more reliable, more people supported Source DÃ¢â¬â¢s point of view. It is extremely useful in showing attitudes towards womenÃ¢â¬â¢s suffrage and, taking into consideration that the newspaperÃ¢â¬â¢s main aim is to report on current affairs, the story must be more dependable and factual. Being a popular tabloid also gives us a deeper insight to the views of the public, as the writerÃ¢â¬â¢s opinions would mirror those of the public-therefore, as the writerÃ¢â¬â¢s views were negative, it means the publicÃ¢â¬â¢s were too. In conclusion, Source D is more reliable for investigating peopleÃ¢â¬â¢s attitudes in 1910 towards the Suffrage campaign. How to cite Which is the more reliable source for investigating peopleÃ¢â¬â¢s attitudes in 1910 towards the campaign?, Papers
Thursday, April 30, 2020
Many such as Benjamin Franklin urged colonial alliance. During the wars first year, Franklin published his famous Join or Die cartoon in Philadelphia, which strongly urged unity amongst the colonies. Due to poor battle tactics, Britain suffered early losses. The losses deteriorated the image of the British as an invincible force in the eyes of the colonists. It showed an underlying layer of weakness, which distanced the colonists from their mother country, Britain.While the actual war served as a tally for the unification of the colonies, the results of the war also had large effects on their identity as a new nation. The victory increased colonial self-esteem, and helped the colonists to perceive themselves as independent people who could defend themselves. Like the French and Indian War, The Proclamation of 1763 was a cardinal event In the development of the colonists sense of identity and unity. The Proclamation declared that settling west of the Appalachians was illegal to colonists. We will write a custom essay sample on Unity and Identity in the Colonies or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page The land was declared off limits because it was Indian land, and the King did not want to cause any more dispute between Britain and the Indians. The colonists found this law to be unacceptable. Colonies had already begun planning on settling west, and found that giving land to the Indians was defeating the purpose of the French and Indian War which they had just fought In. Colonies had come to realize their Independence and self-sufficiency. They rebelled against the law, and proceeded In settling westward.Thomas Pains Common Sense is arguably one of the greatest influences on the unity and identity of the colonists. Thomas Pains pamphlet brought the possibility of Revolution Into full focus for the colonists. The writings placed blame for the suffering of the colonies solely on King George Ill, the current British ruler. Paine beseeches the Idea of an Immediate declaration of Independence, Implying that America had a moral obligation to secede from the corrupt nation. Common Sense rather inspired colonists to initiate secession from Britain, and lead to the writing of the Declaration of Independence.
Friday, March 20, 2020
A Well-Thought Framework, Amendments, and Judicial Review Have Helped the Constitution of the United States of America Stand the Test of Time- essay that got 2nd place for a scholarship!
A Well-Thought Framework, Amendments, and Judicial Review Have Helped the Constitution of the United States of America Stand the Test of Time- essay that got 2nd place for a scholarship! Framework of the ConstitutionThe Constitution of the United States of America has stood the test of time. The Founding Fathers' forethought as they deliberated and worded the Constitution, amendments by Congress, and judicial review by Supreme Courts over the years have helped the Constitution endure. Although the "fount of all authority,"1 it has also proven to be flexible, capable of meeting the different interests of generations of Americans.In 1787, the Constitution's authors philosophically pondered what constitutes good government. Many delegates believed the document which emerged from the Constitutional Convention had established sufficient 'checks and balances' - governmental power divided between the federal government and the States, and the powers assigned to the federal government divided among the Legislative, Executive and Judicial Branches. Federalists debated the merits of a strong federal government, but anti-Federalists claimed a too powerful central government wou ld usurp state sovereignty. In 1791 in response to anti-Federalists' fears, ten amendments (the Bill of Rights) were added to limit the Federal government's power, and to protect individual citizens' liberties such as freedom of speech, freedom of religion, the right to trial by jury with counsel, private property and the privacy of their homes.English: 15th Amendment of the United States Const..."By liberty, was meant protection against the tyranny of the political rulers."2Amending the Constitution to meet the needs and demands of "the people" helped the Constitution endure. After the Civil War, three amendments were added. The Thirteenth Amendment, in 1865, abolished slavery and involuntary servitude; in 1868, the Fourteenth Amendment was ratified with the purpose of protecting any person within a state's jurisdiction from being deprived "of life, liberty, or property without due process of law," [or denied] "the equal protection of the laws."3 The Fifteenth Amendment, in 1870, p rohibited federal and state governments from abridging a citizen's right to vote "on account...
Wednesday, March 4, 2020
Writing Tips Percent, Per Cent and Percentages - Get Proofed! Percent, Per Cent and Percentages WeÃ¢â¬â¢ve been told that putting 110% into anything is mathematically impossible. But weÃ¢â¬â¢re proofreaders, not mathematicians! As such, weÃ¢â¬â¢re not going to let math get in the way of putting everything we have into solving your writing problems. Today, for example, weÃ¢â¬â¢re looking at writing percentages. Words and Numbers As with any numbers, percentages can be written as either words or numbers: Words: Around nine percent of people dislike coffee. Numbers: Approximately 91% of people like coffee. The examples above reflect three important guidelines when writing percentages: Numbers up to ten are usually written as words, while larger numbers are written as numerals When a percentage is written as a word, it should be followed by Ã¢â¬Å"percentÃ¢â¬ When a percentage is written as a numeral, it should be followed by the Ã¢â¬Å"%Ã¢â¬ sign However, this can vary depending on the context (e.g., measurements in scientific writing are almost always written as numerals, even for numbers under ten). ItÃ¢â¬â¢s therefore a good idea to check your style guide for advice on how to write percentages. Percent vs. Per Cent The question weÃ¢â¬â¢re asked most often about writing percentages is whether to use Ã¢â¬Å"percentÃ¢â¬ or Ã¢â¬Å"per cent.Ã¢â¬ Ultimately, though, this doesnÃ¢â¬â¢t really matter: both are accepted spellings of this term. Again, we recommend checking your style guide if you have one, as some publishers and colleges have a preference. And Ã¢â¬Å"percentÃ¢â¬ is much more common these days than Ã¢â¬Å"per cent.Ã¢â¬ But other than that, the main thing is picking one spelling and using it consistently throughout your work. Percent vs. per cent When to Use Ã¢â¬Å"PercentageÃ¢â¬ Finally, we have the word Ã¢â¬Å"percentage.Ã¢â¬ Although similar to Ã¢â¬Å"percent,Ã¢â¬ this word has a slightly different usage: Ã¢â¬Å"PercentÃ¢â¬ is used with specific numbers, while Ã¢â¬Å"percentageÃ¢â¬ is used when referring to a general or non-specific amount of something. For example: A small percentage of the forms were coffee stained. Almost seven percent of the forms were coffee stained. As shown above, you should use Ã¢â¬Å"percentageÃ¢â¬ when the exact amount is unspecified.
Monday, February 17, 2020
Muscular Distrophy - Essay Example The National Institute of Neurological Disorders and Stroke (NINDS) has defined muscular dystrophies (MD) as Ã¢â¬Å"a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. Some forms of MD are seen in infancy or childhood, while others may not appear until middle age or later. The disorders differ in terms of the distribution and extent of muscle weakness (some forms of MD also affect cardiac muscle), age of onset, rate of progression, and pattern of inheritanceÃ¢â¬ (NINDS, 2010, par. 3). There are various types with corresponding clinical manifestations and therapy for MDs. In this regard, the essay aims to compare and contrast, one particular type, the Duchenne MD with another type, the Facioscapulohumeral MD. The causes, pathology and treatment would be discussed and evaluated in light of the two identified MDs. The Duchenne MD is considered the most common form of MD afflicting children, identified to occur in 1 out of 3,500 live male births (London, et.al. 2007, 1791). This type of MD, likewise known as pseudohyperthophy Ã¢â¬Å"refers to enlargement of muscles as a result of their infiltration with fatty tissueÃ¢â¬ (London, et.al. 2007, 1791). The disorder usually appears within the first three to four years of the childÃ¢â¬â¢s development. In a research conducted by Bogdanovich, et.al. (2005), the authors averred that Ã¢â¬Å"DMD is characterized by progressive and severe muscle loss that leads to loss of ambulation, with those affected often becoming wheelchair dependent toward the end of the first decade of life. The disease is caused by mutations in the DMD gene resulting in quantitative and/or qualitative disturbances in expression of the gene product, dystrophinÃ¢â¬ (par. 1). The symptoms for Duchenne MD include any or a combination of the following: Ã¢â¬Å"fatigue, mental retardation (possible, but does not worsen over time), muscle weakness, and